How often the body reads genes varies greatly and is also influenced by environmental influences, diet and lifestyle. There are possibilities that genes cannot be read. One reason for this is DNA methylation, which serves to regulate metabolic processes. For example, more or less of an enzyme is produced. Important genes in sport are TNF alpha or interleukin 6 (IL 6). If these genes are too low in methylation, low-grade inflammation occurs, which inhibits performance. The methylation level in Line 1 reflects the total methylation in the body and provides initial indications of an increased need for methyl donors such as folic acid (Hunter et al., 2019). Environmental influences and diet can change methylation and thus gene activity. 
Another possibility for regulation are miRNAs. These are short pieces of RNA that control signal transduction. miRNAs are very rapid regulatory mechanisms. A change in miRNAs can be measured after just 1 day of sports intervention. An appropriate increase in training or a possible additional need for secondary plant ingredients or vitamins can be recognized. You can determine whether the body is already at its limits or can be challenged even further. miRNAs reflect the current training status and can enable rapid interventions and adjustments to the training plan.